עבריתHow CBD can help you be reduce symptoms and ailments of different diseases
- Wednesday, March 17 2021 at 18:22
- Snir Mutzafi
- CBD
- 7 minutes
CBD's course of effect is slower - do not expect immediate results, the level of influence and character changes in accordance to the type of strain, cannabinoid ratio, dose and consumption method you will use. What qualities CBD can or be assumed to provide for you as a patient?
CBD studies in rats, tested CBD given via injections, transdermal (on the skin), and orally, deduced that CBD may help reduce pain in Arthritis by influencing endocannabinoid receptor activation, thus reducing pain through:
Not only does depression and anxiety are marked as an "epidemic" in western/first-world countries, but depression is also overwhelmingly a leading cause of disability. The problem people face dealing with anxiety and depression is not only the disorders themselves, but the serious side effects and long-term effects modern treatment in the form of pharmaceutical drugs offer, which include:
So what evidence exists of CBD‘s usefulness in treating anxiety and depression? Rodents A 2010 and 2016 studies support the suggested attribute of CBD's anti-depressive effect on rodents, this article (which I HIGHLY recommend since it reviews all known studies regarding anxiety and CBD in rodents - marks it as promising. Humans A significant reduction in anxiety during public speaking was recorded after taking 600mg of CBD compared to a placebo, another study demonstrated lower levels of anxiety with half the previous dose - 300mg. This reviews 49 published studies and summarizes for you lazy bastards (table 2) also supports the notion of CBD's efficacy in reducing anxiety in several disorders. Both rodent and human studies have shown CBD to reduce signs of anxiety and depression, further trials are needed but the advantages CBD might offer compared to other anti-depressants:
Researchers are examining CBD's potential to treat or prevent neurodegenerative diseases by its effect on the CB1 receptor - that includes:
With its neuroprotective and anticonvulsant properties, research has been done testing CBD's effect on Seizures in epilepsy, in this study - there were 36.5% fewer seizures per month! A 12 weeks study (noted "severe adverse effects" in 12% of the subjects). Fiction is already a well-based reality\\, a CBD based drug - Epidiolex has been approved in June 2018 by the FDA to treat a severe form of epilepsy in children aged 2 and above:
The Israeli perspective adds volume to the matter, 66 out of 74 patients (89%!) reported a reduction in their seizure frequency during 3 months to follow-up using CBD to THC ratio of 20:1 (2 strains - 'Cheese Pie' and 'Avidekel'). Another one, conducted by Professor Uri Kramer of Tel-Aviv University on 92 patients (79% of them aged 1 to 17), follow-up ranged from 3 to 45 months, based upon parent's report - "improvement" measured in the percentage of seizures reduction:
There is a well-known association between consuming "Cannabis" and psychosis, but what about CBD-rich cannabis strains with either low THC content or negligible ones? Consuming high CBD - content Cannabis was found associated with "lower degrees of psychotic symptoms". Supporting the claim of CBD's antipsychotic nature, as early as 1995, a daily dosage of 1500 mg of CBD in a 19-year-old female schizophrenic resulted in an improvement of her psychotic symptoms. In comparison to antipsychotic medicine, CBD compared to Amisulpride was found to be "as effective" in the treatment of symptoms with fewer side effects. In two other studies with opposite results including a placebo group, CBD in patients with acute psychosis displayed improvement in some parameters, while another found no difference between CBD and placebo on psychotic symptoms and cognitive performance.
CBD combined with THC displayed a "significant analgesic effect" in 15 out of 18 trials examining cannabinoids effects on pain in malignant diseases.
Your brain is the control center of nausea and vomiting, this center includes receptors (Dopamine D2 and Serotonin 5-HT3) that monitor the GI system, modern antiemetics such as:
These commonly used medications work on different receptors in the brain in charge of vomiting. Their side effects include:
There are certain psychological disorders not caused by physical factors manifested in prolonged sessions of nausea and vomiting. Some smells, visuals, motion sickness, and emotions can induce nausea and as a result – vomiting. CBD may help treat symptoms caused by cancer treatment - Chemotherapy - whether radiation or drugs – like nausea and vomiting by inhibiting an enzyme that breaks Anandamide - prolonging CB1 receptor activity. 7 Patients suffering from CINV (Chemotherapy-Induced Nausea and Vomiting) were given "CMB" - cannabis containing THC and CBD - another group (9 patients) was given a placebo, in comparison:
A person can be inflicted by Insomnia due to a variety of reasons and factors:
SOME can interrupt / change sleep cycles (such as SSRIs and Benzodiazepines) - CBD appears to not interfere with the sleep cycle of healthy individuals. Sleep cycle disturbances – CBD can improve complex sleep-related behaviors associated with rapid eye movement sleep behavior disorder in Parkinson's disease patients: A case series - CBD improved sleeping in Parkinson's patients with REM sleep (Rapid Eye Movement). 409 people with insomnia using an app recorded their insomnia severity before and after consuming cannabis (CBD included) was associated with symptom relief greater than even THC. Even in clinical wards – CBD improved sleep scores in psychiatric patients within the first month of consumption in most subjects (66%), 48 out of 72 adult patients.
Similar to Vitamin E's antioxidant properties for skin health, CBD, as mentioned above, holds an anti-inflammatory effect, thus improving skin health which may improve skin aesthetics (wrinkles and age lines).
Topical use of CBD-rich ointments in people with skin disorders and scars improved quality of life measured by:
CBD was found to:
CBD among, other phytocannabinoids displayed anti-proliferating quality (CBD along CBG had the greatest activity), It can potentially delay cell growth processes, and slow down the development and spreading of Psoriasis to other areas in the body.
Inhibition of proliferation of keratinocytes, marking it as a therapeutic potential in Atopic Dermatitis - reducing itchiness and loss of sleep. CBD has many different health and therapeutic applications and attributes that have and will surely be further researched in the future\\, the potential is too big even for big pharma to try and bury it under the fold of other drugs and medications – CBD offers a huge market draw.